Clinical QuickieDermatology
Urticaria vs Anaphylaxis
Hives are skin findings. Anaphylaxis is a systemic syndrome.
Urticaria is transient and migratory
Individual wheals typically appear and fade within hours, often moving to new locations.
Anaphylaxis involves more than skin
Airway, breathing, circulation, or significant GI involvement after a likely trigger can establish anaphylaxis even if hives are absent.
Epinephrine is first-line for anaphylaxis
Antihistamines may improve itching/hives but do not treat airway edema or shock.
Find the trigger, but do not delay treatment
Food, medications, stings, latex, and other exposures matter after immediate stabilization.
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