Clinical QuickieEndocrine/Metabolic
Hyperglycemia vs Hypoglycemia
The glucose number matters — but the symptoms, medications and mechanism matter more.
Hyperglycemia: ask why now
Missed medication, steroids, infection, dehydration, stress physiology and diabetes progression are common triggers.
Hypoglycemia: identify the drug and timing
Insulin and sulfonylureas are common culprits; poor intake, alcohol, renal dysfunction and medication changes increase risk.
Know the dangerous syndromes
DKA can occur with only modest glucose in selected patients, especially with SGLT2 inhibitors. HHS is marked by severe hyperglycemia and hyperosmolar physiology.
Prevent recurrence
Treating one low or one high is not enough. Adjust the regimen, intake, monitoring and precipitating factors.
Want more depth?
Read the Deep Dive