Clinical QuickieHematology/Coagulation

Hemoglobin & Hematocrit

The trend often tells you more than the value.

Low Hgb/Hct Quantifies Anemia — Not the Cause

Use baseline, rate of change, symptoms, MCV/RDW, reticulocyte response, kidney function and evidence of blood loss or hemolysis.

The value tells you anemia is present; the workup tells you why.

Volume Status Can Fool You

Hemoconcentration can raise Hgb/Hct; IV fluids can lower them by dilution.

A post-fluid decline is not automatically ongoing bleeding.

Acute Blood Loss Can Lag

Early hemorrhage may initially show a near-baseline hemoglobin before redistribution and resuscitation change the concentration.

A reassuring early hemoglobin does not rule out significant acute blood loss.

Organize the Mechanism

Think blood loss, underproduction, hemolysis and mixed processes.

CKD-associated anemia is often normocytic, but concurrent deficiencies are common.

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