Clinical QuickieNeurology

Headache — Primary vs Secondary

The most important headache question is often: is this different from usual?

Classify the familiar patterns

Migraine, tension-type, and cluster headaches have recognizable features, but overlap occurs.

Screen for secondary red flags

Thunderclap onset, focal neurologic deficits, meningismus, papilledema, pregnancy/postpartum context, cancer/immunocompromise, trauma, or major pattern change require a different pathway.

Imaging is not automatic

Stable recurrent migraine with a normal neurologic exam and no red flags usually does not need routine imaging.

Watch for medication-overuse headache

Frequent acute-medication use can transform episodic headache into a more persistent problem.

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